20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T76182 | Phospholipase A2 | ||
Phospholipase A2 (PLA2), a heat-stable, calcium-dependent enzyme class member, catalyzes the hydrolysis at the sn-2 position of membrane glycerophospholipids, releasing arachidonic acid (AA). It is frequently utilized in... | |||
T17218 | Varespladib methyl | A-002,LY333013 | Others , Phospholipase |
Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor. | |||
T16751 | Rilapladib | SB 659032 | Phospholipase |
Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating factor receptor. | |||
TN1419 | Rhamnetin | beta-Rhamnocitrin | Others , Phospholipase |
Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities. Rhamnetin inhibits secretory phospholipase A2. | |||
T21907 | PACOCF3 | 1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone | Phospholipase |
PACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromet hylketone) is an inhibitor of Ca(2+)-independent phospholipase A2(PLA2) with an IC 50 of 3.8 μM. PACOCF3 alters Ca 2+ signaling in renal tubular cells [1] [2]... | |||
T6109 | Darapladib | SB-480848 | Phospholipase |
Darapladib (SB-480848)(IC50=0.25 nM) is a substituted pyrimidone with inhibitory activity towards lipoprotein-associated phospholipase-A2 (Lp-PLA2). | |||
T31204 | Darapladib-impurity | Others | |
Darapladib-impurity is the impurity of Darapladib. Darapladib inhibits lipoprotein-associated phospholipase A2 (Lp-PLA2). | |||
T21815 | ONO-RS-082 | Others | |
ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor. | |||
T9753 | LEI110 | Phospholipase | |
LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT). | |||
T11874 | Lp-PLA2-IN-3 | Phospholipase | |
Lp-PLA2-IN-3 is a potent and orally bioactive lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor that inhibits recombinant human Lp-PLA2 with an IC50 value of 14 nM. | |||
T5454 | N-(p-amylcinnamoyl) Anthranilic Acid | ACA | Phospholipase , TRP/TRPV Channel |
N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker. | |||
T19729 | Dodecylphosphocholine | DPC,n C12PC,Foscholine-12,DDPPC,nC12PC,n-C12PC | Others |
Dodecylphosphocholine (DPC) is a substrate-type inhibitor of pancreas phospholipase A2. Dodecylphosphocholine is a detergent. | |||
T24449 | Mepacrine | Haffkinine,Erion | Others |
Mepacrine (Erion) is an acridine derivative formerly widely used as an antimalarial. It is used in cell biological experiments as an inhibitor of phospholipase A2. | |||
T2044 | Varespladib | LY315920 | Phospholipase |
Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusiv... | |||
T21606L | Anti-Inflammatory Peptide 1 Acetate | Anti-Inflammatory Peptide 1 Acetate(118850-70-8 Free base) | Phospholipase |
Anti-Inflammatory Peptide 1 Acetate (C45H82N12O14S2) possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammati... | |||
T14689 | BMS493 | BMS-493 | Phospholipase , Retinoid Receptor |
BMS493 is an inverse agonist of the pan-retinoic acid receptor (RAR) that inhibits retinoic acid-induced differentiation, enhances the interaction of nuclear co-inhibitors with RARs, attenuates RA signaling, potentiates ... | |||
TN1064 | Aristolochic acid C | Others | |
Aristolochic acid C could as the larval feeding stimulants. | |||
TN6993 | Benzylideneacetone | Benzalacetone | Phospholipase , Endogenous Metabolite |
Benzylideneacetone, a monoterpene produced by the insect pathogenic bacterium Xenorhabdus nematophila, is a phospholipase A2 (PLA2) inhibitor with inhibitory effects on arachidonoid biosynthesis and enhances baculovirus ... | |||
T0370 | Pheniramine maleate | Daneral,Inhiston,Trimetose | 5-HT Receptor , Histamine Receptor |
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... | |||
T10017 | 1-Linoleoyl Glycerol | Glycerol 1-monolinolate,Monolinolein,Glyceryl monolinoleate,1-Linoleoyl-rac-glycerol | Phospholipase |
1-Linoleoyl Glycerol (Monolinolein) is fatty acid glycerol that has been isolated from Saururus Chinensis roots. The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl Glycerol exhibit Lipoprotein-associated phospholipase A2 (... |